Evaluating the therapeutic response of intra-vitreal moxifloxacin in acute post-operative (cataract) endophthalmitis.

نویسندگان

چکیده

Objective: To assess the effectiveness and side effects of injecting intra-vitreal moxifloxacin (IV-M) in treatment acute post‑operative (cataract) endophthalmitis having visual acuity ≥ hand movements. Study Design: Prospective, Interventional Case Series study. Setting: Eye Department Qazi Hussain Ahmad Medical Complex, Nowshera. Period: 2018 to Jan. 2021. Material & Methods: Thirty (30) patients with post‑op who presented within 4 weeks (VA) movements (HM) received two IV-M injection. at 24 hr. interval an department. Patients prior history ocular diseases or intra-vitreals were excluded. followed up 12 either for improvement deterioration endophthalmitis. No. attained VA 6/12 6/60 12th week visit compared no. presentation, by performing statistical analysis. In addition, pre-therapy converted into logarithm minimum angle resolution (Log MAR) time presentation was post-therapy end using repeated measure ANOVA test. Results: Twenty five (83.3%) completely resolved while underwent core vitrectomy. 14 (46.66%) 22 (73.34%) achieved 6/60, respectively as 04 (13.33%) 08 (26.66%) (p = 0.043). same way, mean Log MAR pre-intervention 0.811 which improved 0.344 (P < 0.05). We didn’t observe any toxicity IV-M. Conclusion: Intra-vitreal efficacious safe post-operative

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ژورنال

عنوان ژورنال: The professional medical journal

سال: 2022

ISSN: ['1024-8919', '2071-7733']

DOI: https://doi.org/10.29309/tpmj/2022.29.10.7134